Donald A Bruun Selected Research

tetramethylenedisulfotetramine (DSTA)

12/2021	Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus.
1/2020	Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice.
8/2015	Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures.
1/2015	Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine.
5/2012	Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine.

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Donald A Bruun Research Topics

Disease

14	Seizures (Absence Seizure) 11/2020 - 06/2011
12	Status Epilepticus (Complex Partial Status Epilepticus) 12/2021 - 10/2016
10	Neuroinflammatory Diseases 12/2021 - 12/2014
3	Brain Injuries (Brain Injury) 12/2021 - 04/2015
3	Gliosis 11/2020 - 01/2020
3	Cognitive Dysfunction 01/2019 - 10/2016
3	Asthma (Bronchial Asthma) 04/2013 - 03/2008
2	Poisoning 12/2021 - 01/2019
1	Neurodevelopmental Disorders 12/2020
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 12/2020
1	Mood Disorders (Mood Disorder) 01/2017
1	Atrophy 01/2017
1	Skin Abnormalities 12/2014
1	Bradycardia 05/2010

Drug/Important Bio-Agent (IBA)

12	Isoflurophate (DFP)FDA Link 12/2021 - 06/2011
9	OrganophosphatesIBA 12/2021 - 06/2011
5	tetramethylenedisulfotetramine (DSTA)IBA 12/2021 - 05/2012
4	Atropine FDA LinkGeneric 12/2021 - 07/2012
4	Nerve AgentsIBA 12/2021 - 04/2015
4	Diazepam (Valium)FDA LinkGeneric 11/2020 - 12/2014
3	BenzodiazepinesIBA 12/2021 - 11/2020
3	Proteins (Proteins, Gene)FDA Link 12/2021 - 10/2016
3	Midazolam (Versed)FDA LinkGeneric 12/2021 - 11/2020
3	Cholinesterase Inhibitors (Anticholinesterases)IBA 11/2020 - 10/2016
2	Chlorpyrifos (Lorsban)IBA 12/2020 - 05/2010
2	PesticidesIBA 12/2020 - 05/2010
2	Pregnanolone (Allopregnanolone)IBA 11/2020 - 08/2015
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 10/2016
2	Glial Fibrillary Acidic ProteinIBA 01/2017 - 10/2016
2	CalciumIBA 10/2016 - 08/2015
2	Neuroprotective AgentsIBA 01/2016 - 04/2015
2	ConvulsantsIBA 01/2015 - 05/2012
2	Parathion (Ethyl Parathion)IBA 04/2013 - 05/2010
2	Cholinergic Agents (Cholinergics)IBA 07/2012 - 06/2011
1	OximesIBA 12/2021
1	AMPA Receptors (AMPA Receptor)IBA 11/2020
1	Drug CombinationsIBA 11/2020
1	perampanelIBA 11/2020
1	fluoro-jade CIBA 11/2020
1	pralidoxime (Protopam Chloride)FDA Link 11/2020
1	PicrotoxinIBA 01/2020
1	RodenticidesIBA 01/2020
1	AntidotesIBA 11/2019
1	LipidsIBA 11/2019
1	CytokinesIBA 01/2019
1	2- (6- chloro- 2- (4- (3- fluoropropoxy)phenyl)imidazo(1,2- a)pyridin- 3- yl)- N,N- diethylacetamideIBA 01/2019
1	Hematoxylin (Haematoxylon)IBA 01/2017
1	AcetylcholinesteraseIBA 01/2017
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2017
1	PK 11195 (PK11195)IBA 10/2016
1	LigandsIBA 10/2016
1	Pharmaceutical PreparationsIBA 01/2016
1	Neuregulin-1 (Neuregulin 1)IBA 04/2015
1	GABA Receptors (GABA Receptor)IBA 01/2015
1	PoisonsIBA 01/2015
1	Indicators and Reagents (Reagents)IBA 12/2014
1	thiouredopyrenetrisulfonateIBA 12/2014
1	Coconut OilIBA 12/2014
1	Peanut OilIBA 12/2014
1	Epoxide HydrolasesIBA 12/2014
1	Triglycerides (Triacylglycerol)IBA 12/2014
1	Pyridostigmine Bromide (Pyridostigmine)FDA LinkGeneric 07/2012
1	fluoro jadeIBA 05/2012
1	NeurotoxinsIBA 06/2011
1	Paraoxon (E600)IBA 05/2010
1	Diazinon (Dimpylate)IBA 05/2010
1	AllergensIBA 03/2008

Therapy/Procedure

2	Therapeutics 12/2021 - 01/2020
1	Aftercare (After-Treatment) 05/2012
1	Oral Administration 05/2012
1	Subcutaneous Injections 05/2010